Combine buttermilk and hot sauce in a container. Add the chicken livers and allow them to rest in the buttermilk brine in the fridge for at least an hour.
Preheat your air fryer to 380 degrees Fahrenheit. In a shallow bowl, combine all-purpose flour, creole seasoning, and Italian seasoning. Remove the chicken livers from the buttermilk brine, shaking off any excess buttermilk, and place them in the flour to coat all sides. Shake off excess flour.
Grease the air fryer basket with a little oil. Then place the floured livers in the air fryer basket in a single layer. Close the air fryer basket (do not spray the top of the livers at this point) and cook for 10 minutes.
After 10 minutes, open the basket and spray the chicken livers with oil. Flip and spray again. Continue to cook for an additional 10-15 minutes until the chicken livers are cooked through and have reached an internal temperature of 165 degrees Fahrenheit.
Once done, remove the fried chicken livers from your air fryer basket. Salt and pepper to taste and serve.