Cajun Salmon Alfredo Pasta

Make Cajun Salmon Alfredo Pasta in less than 30 minutes using this easy dinner recipe. It includes seared salmon seasoned with my homemade Cajun Blend (or our salt-free Cajun seasoning) and pasta tossed in my homemade Alfredo sauce.

Why Make This

• Ready in less than 30 minutes: like my Cajun Shrimp and Sausage Pasta, this Cajun Salmon Alfredo takes less than 30 minutes for a flavor-packed meal
• Homemade Alfredo sauce: while you can make this dish with jarred Alfredo sauce, you’ll see that it’s actually easier and more flavorful to use homemade.

Ingredients Needed

Cajun Salmon

• Salmon: I used about 4 fresh salmon filets. If your salmon is frozen, you should thaw it out before cooking it in this dish.
• Cajun Seasoning: When testing this recipe, I used my own cajun spice blend. But, for a salt-free option, you can absolutely use the Cajun Seasoning recipe on this site. You can always salt to taste at the end.
• Butter: I sear the salmon in butter, but you can use olive oil as an alternative.

Alfredo Sauce

• Butter: You can use salted or unsalted butter, depending on your personal preferences. Unsalted butter gives you more control over adding salt to your taste
• Garlic: I use fresh minced garlic
• Heavy Whipping Cream
• Parmesan Cheese: l get this fresh in the refrigerated section of the market. I do not recommend using the shelf-stable parmesan cheese as it is much saltier than fresh grated.
• Cream Cheese: Adding softened cream cheese to alfredo sauce makes it creamy.
• Italian seasoning

Other

• Pasta: I used cooked fettuccine pasta. But, you can use any pasta that you prefer, like penne, in this recipe. Simply cook the pasta according to the package directions.

How to Make Cajun Salmon Alfredo Pasta

1. Season the salmon: add Cajun seasoning to the salmon and rub it evenly all over the fish.
2. Sear the salmon: get a nice brown sear on your salmon in a skillet.
3. Make the Alfredo sauce: in the same skillet that you seared the fish, make the Alfredo sauce. The leftover bits add so much flavor!
4. Add the pasta and plate: this Cajun Salmon Alfredo Pasta isn’t complete without cooked pasta. Toss it in the sauce to coat and plate the dish.

Top Cooking Tips & FAQs

• Adjust the spices if using Cajun seasoning from the store: this recipe uses homemade Cajun seasoning. Homemade spice blends are typically not as salty as Cajun seasoning mixes from the store. So, if you’re using a Cajun seasoning from the store, use about 1/2 tsp per pound. You can always add more to taste at the end.
• Use parmesan from the refrigerated section: this has more flavor and less salt compared to the grated parmesan that you can pick up in the pasta aisle.
• Make this low-carb by using your favorite low-carb noodles: my personal favorites are air fryer spaghetti squash or the hearts of palm noodles I used in Cajun Shrimp Alfredo.
  

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5 from 3 votes

Cajun Salmon Alfredo Pasta

Make Cajun Salmon Alfredo Pasta in less than 30 minutes using a homemade Cajun seasoning and a homemade Alfredo sauce.

Prep Time 5 minutes minutes

Cook Time 25 minutes minutes

Total Time 30 minutes minutes

Servings 4

Ingredients

Cajun Salmon

• 1 lb salmon about 3-4 filets
• 1 tbsp cajun seasoning I'm using my homemade cajun seasoning, but you can find a salt free cajun seasoning
• 2 tbsp butter unsalted or salted, depending on if you would like to be able to salt to taste

Alfredo Sauce

• 1/4 cup butter unsalted
• 5 cloves garlic minced
• 1 cup heavy whipping cream
• 1 ¼ cup Parmesan Cheese from the refrigerated section of the market
• 2 oz cream cheese softened
• 1/2 tsp Italian seasoning

Other

• ½ lb fettuccine pasta cooked according to package directions

Instructions

For the salmon

• Sprinkle the salmon with the cajun seasoning mix and set aside.
• Heat the butter in a non-stick skillet until melted and sizzling over medium heat
• Sear salmon for ~3 minutes per side to cook them through. Keep warm and set aside

For the alfredo sauce

• In the same skillet used for salmon, do not rinse out the skillet. Melt the butter on medium heat
• Add the minced garlic and saute until fragrant (about 2-3 minutes)
• Turn the heat down to medium-low and add the heavy cream and softened cream cheese. Mix until the cream cheese is fully incorporated.
• Add the remaining ingredients to the pan and stir occasionally until the sauce thickens (about 5-7 minutes)

Finish the dish

• Add the pasta to the pan with the alfredo sauce. Use tongs to toss them around and coat them.
• Top the pasta with salmon & serve.
• Optional: finish the plate with parmesan cheese, more cajun seasoning, lemon wedges, parsley, red pepper flakes.

Notes

• Adjust the spices if using Cajun seasoning from the store: this recipe uses homemade Cajun seasoning. Homemade spice blends are typically not as salty as Cajun seasoning mixes from the store. So, if you’re using a Cajun seasoning from the store, use about 1/2 tsp per pound. You can always add more to taste at the end.
• Use parmesan from the refrigerated section: this has more flavor and less salt compared to the grated parmesan that you can pick up in the pasta aisle.
• Make this low-carb by using your favorite low-carb noodles: my personal favorites are air fryer spaghetti squash or the hearts of palm noodles I used in Cajun Shrimp Alfredo.